A drug-induced photosensitive reaction most commonly appears as an exaggerated sunburn. It occurs when a person takes certain medications or applies, either intentionally or unintentionally, offending substances to the skin and is exposed to ultraviolet radiation. A photosensitive reaction should be considered in people experiencing sunburn of greater severity than would normally be expected for them, or who develop rashes in areas exposed to the sun or tanning unit.

Drug-induced photosensitive reactions can occur in anyone, though to widely varying degrees of severity. People with fair complexions; red, blonde or light brown hair; blue or green eyes; and who generally sunburn easily and do not tan are most at risk. A history of severe sunburn(s) may also increase the risk, as may a history of allergies, especially contact hypersensitivities, to cosmetics or other topical agents.

Visit our list of the most common photosensitizing materials. This is not a list of every material that could have photosensitizing effects. Again, if there is any question about a drug or product that you use, you should consult a physician or pharmacist.